CYP2D6 Phenotype Influences Aripiprazole Tolerability in Pediatric Patients with Mood Disorders

Efficacy and Tolerability of Aripiprazole in Patients with Schizophrenia & Schizoaffective Disorders

Before the 1990s, treatment of psychoses centred on conventional agents whose tolerability was limited by extrapyramidal symptoms (EPS). The past decade has seen the emergence of newer generation of antipsychotic agents. These agents provide better negative symptom efficacy, less impaired cognition and lower risk of extrapyramidal syndromes. Aripiprazole, a new atypical antipsychotic drug, disp...

Efficacy and tolerability of Aripiprazole in Patients with Schizophrenia & Schizoaffective Disorders

I wish to make the following observations about the article ‘Fidelity of ECT devices: An alert to clinicians’ (Andrade, 2003), published in the October-December 2003 issue of the Indian Journal of Psychiatry: 1. The authors of the paper, besides myself, are Kurinji S., Research Officer, Department of Psychopharmacology, and G. Laxmanna, Biomedical Engineer, Department of Biomedical Engineering,...

Tolerability of high-dose aripiprazole in treatment-refractory schizophrenic patients.

Trait impulsivity in patients with mood disorders.

BACKGROUND Impulsivity is a key component of the manic behavior of bipolar disorder and is reported to occur in bipolar patients as a stable characteristic, i.e. a trait. Nevertheless, impulsivity has not been widely studied in depressed bipolar patients. We assessed impulsivity in depressed and euthymic bipolar and unipolar patients and healthy controls. We hypothesized that bipolar subjects w...

Mood disorders in patients with epilepsy.

Epilepsy is a common disabling neurological disorder associated with increased rates of mood disorders especially depression as compared to the general population. Most antidepressants at therapeutic dosages exhibit a seizure risk. Some antidepressants may also display antiepileptic effects, especially at low doses, but the mechanism of this action is largely unknown. In general, the new antide...